PLAU anticorps

N° du produit ABIN7670720

Cet anticorps Rat Monoclonal détecte spécifiquement PLAU dans ELISA (Capture). Il présente une réactivité envers Humain.

Aperçu rapide pour PLAU anticorps (ABIN7670720)

Antigène: PLAU (Plasminogen Activator, Urokinase (PLAU))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp PLAU est non-conjugé

Application: ELISA (Capture)

Clone: 7A1

Détail du produit anti-PLAU anticorps

Fonction: Plasminogen Activator/Urokinase Monoclonal Antibody(Capture)

Purification: Protein A/G Purification

Immunogène: Recombinant Human Plasminogen Activator/Urokinase protein expressed by Mammalian

Isotype: IgG1

Information d'application

Indications d'application: ELISA Capture 2-8 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Date de péremption: 12 months

Détails sur PLAU

Antigène: PLAU (Plasminogen Activator, Urokinase (PLAU))

Autre désignation: Plasminogen Activator/Urokinase

Sujet: UPA,u-PA,ATF,URK,UP-A,Urokinase,Abbokinase,This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: P00749

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration